There are two different opinions on the making of Nylon. They are as below:
Nylon” came from “New York” and “London”, because two chemists thought up the word on an intercontinental flight from one of the cities to the other. New York (NY)+London(LON)=NYLON.
The word nylon, it’s actually quite arbitrary. DuPont itself has stated that originally the name was intended to be No-Run (that’s run as in the sense of the compound chain of the substance unravelling), but at the time there was no real justification for the claim, so it needed to be changed. Since the products were not really run-proof, the vowels were swapped to produce “nuron”, which was changed to “nilon” “to make it sound less like a nerve tonic”. For clarity in pronunciation, the “i” was changed to “y”. So finally what we got is the word Nylon.